Temperature monitoring and model optimization of rabbit chest extracorporeal microwave irradiation
- VernacularTitle:兔胸部微波照射中的温度监测与照射方式优化
- Author:
Zhengping ZHANG
;
Dianzhong ZHANG
;
Xiuchun QIU
;
Yanhua WEN
;
Yunyan LIU
;
Qingyu FAN
- Publication Type:Journal Article
- Keywords:
Microwave irradiation;
Temperature monitoring;
Rabbit
- From:
Chinese Journal of Radiation Oncology
2008;17(5):377-380
- CountryChina
- Language:Chinese
-
Abstract:
Objective To clarify the temperature curve of the irradiation target area,its adjacent tissue and the whole body during extracorpereal microwave irradiation, then to compare and optimize different irradiation models. Methods Different parts of the chest of adult New Zealand white rabbit were irradiated using different extracorporeal microwave irradiation models. The temperature of the irradiated skin, the subcutaneous and deep parts, the adjacent tissues and the anus was measured. The experiment was bi-factor and multi-level designed according to the repeatedly measured data and the rabbits was divided into group a,b,c and d. Results The increase rate of the surface temperature in the dorsal lung was similar between group d and group b1(F=10.04,P<0.01). However,the increase rate of the surface temperature in the ventral lung of group d was lower, and the mean temperature of this site measured 10 minutes later was also lower than group b1(F=10.04,P<0.01). The increase rate of the rectal temperature of group d was higher,and the mean rectal temperature tested 10 minutes later was also higher than group b1(F=7.04,P<0.01). Conclusions Multi-array irradiation could achieve satisfactory irradiation depth and appropriate therapeutic temperature. Well controlled extracorporeal microwave irradiation under is an ideal thermotherapy method.
