Progress on epigenetic research of hepatocellular carcinoma
- VernacularTitle:肝细胞癌的表观遗传学研究进展
- Author:
Qingqi HONG
;
Junyao XU
- Publication Type:Journal Article
- Keywords:
hepatocellular carcinoma;
epigenetics;
DNA methylation;
histono modification
- From:
International Journal of Surgery
2008;35(9):642-644
- CountryChina
- Language:Chinese
-
Abstract:
The incidence and mortality of hepatocellular carcinoma have increased in recent decades. Although the major etiological factors have been identified, the exact molecular biology mechanism remains unclear. Re- cently, more and more evidences prove that epigenetics mechanism plays an important role in hepatoceUular carcino-ma. Here we try to make a progress on the abnormal epigenetics changes, epigenetics detection and treatments of hepatocellualr carcinoma.