Funtion of cytokine in pathogenesy of severe acute pancreatitis
- VernacularTitle:细胞因子在重症急性胰腺炎发病机制中的作用
- Author:
Shengbo JIANG
;
Zhongdong ZOU
;
Lie WANG
- Publication Type:Journal Article
- Keywords:
severe acute pancreatitis;
cytokine
- From:
International Journal of Surgery
2008;35(9):604-606
- CountryChina
- Language:Chinese
-
Abstract:
Severe acute pancreatitis is the systemic inflammatory reaction caused by the preternatural activation of trypsogen. The necrotizing pancrea as the antigen or stimulant, activiates immunocyte and in-flammatory cell to release a great deal of cytokines, including proinflammatery factor and anti-inflammatory factor. The former aggravates the damage of constitution, the latter could antigonize the damage of anti-inflam-matory factor. The unbalance of pro-and anti-inflammatory cytokines ,leads to the occurrence of systemic in-flammatory syndrome, even the mutiple organ failure.
