Adult endodermal sinus tumor of testis:report of 6 cases
- VernacularTitle:成人睾丸内胚窦瘤诊治经验
- Author:
Li LU
;
Jianhui MA
;
Changling LI
- Publication Type:Journal Article
- Keywords:
Endodermal sinus tumor of testis,adult;
Chemotherapy,adjuvant
- From:
Chinese Journal of Urology
2008;29(10):708-711
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the diagnosis and outcome of adult endodermal sinus tumor oftestis.Methods The clinic data of 6 cases of adult endodermal sinus tumor of testis were reviewed.The patients' average age was 28 years.Five patients complained of an asymptomatic scrotal mass and1 patient complained of the pain of cryptorchidism.All patients received radical orchiectomy as initialtreatment.Pathology results suggested 2 patients with stage Ⅰ disease,3 patients with stage Ⅱ diseaseand 1 patient with stage Ⅲ disease.All were treated with chemotherapy or radiotherapy following rad ical orchiectomy.Retroperitoneal lymph node dissection(RPLND)was performed in Ⅰ case with stageⅡ disease.Results Six cases of adult endodermal sinus tumor of testis were confirmed by patholo gy.Five patients were followed up for 1.5 year to 8 years,no local recurrence and distant metastasiswere found.Conclusions Adult endodermal sinus tumor is a rare neoplasm of the germinal cell line.Pathological examination is the key to diagnosis.Postoperative combination chemotherapy and radio therapy are the most common means of this disease.