Prediction of esophageal varices in patients with liver cirrhosis
- VernacularTitle:肝硬化患者食管静脉曲张的临床预测
- Author:
Sheng ZHENG
;
Yubo WANG
;
Hai LIU
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
Esophageal and gastric varices;
Platelct count;
Spleen index
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(28):29-32
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study whether clinical variables could be used to predict the presence of esophageal varices(EV). Methods One hundred and twenty-six patients with decompensated liver cirrhosis were enrolled. Upper endoscopy was performed to identify the EV. The spleen vein (SV), portal vein(PV), spleen index(SI), ascites was determined by ultrasenography. Platelct count(Pt), prothrombin time(PT) and liver function was determined. Results Ninety-five patients with EV, and 42 patients with severe EV. Patients with EV had significant larger SI and lower Pt. Pt and SI were predictive factors for the presence of EV. When SI≥66.9 cm2 and Pt≤89.0×109/L, they had a positive predictive value of 97.4% and 96.5%, and a negative predictive value of 55.4% and 59.8%, respectively. SI was the only predictive factor for the presence of severe EV. When SI≥82.6 cm2, it had a positive and negative predictive value of 89.2% and 75.4%. Conclusions Pt and SI are predictive factors for the presence of EV. SI is the only predictive factor for the presence of severe EV. Non-invasive factors SI and Pt can be used to predict the EV in patients with decompensated liver cirrhosis.
