Analysis of pathogen spectra and their drug resistance in patients with enterocutaneous fistula complicated with abdominal infection
- VernacularTitle:肠外瘘并发腹腔感染的致病菌谱与耐药性分析
- Author:
Zheng ZHOU
;
Jianan REN
;
Gefei WANG
;
Xinbo WANG
;
Chaogang FAN
;
Jieshou LI
- Publication Type:Journal Article
- Keywords:
Enterocutaneous fistula;
Surgical infection;
Antibiotics;
Drug-resistance;
Pathogenic bacterium
- From:
Chinese Journal of Digestive Surgery
2008;7(5):331-333
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the pathogen spectra in patients with enterocutaneous fistula complicated with abdominal infection and their resistance to antibiotics. Methods The abdominal pus was collected from 226 patients with enterocutaneous fistula complicated with abdominal infection for bacterial culture and antibiotic susceptibility test. Results A total of 520 bacterial strains were harvested, including 333 strains of gram-negative bacteria, I 80 strains of gram-positive bacteria and 7 strains of fungi. The top 10 bacteria cultured were Escherichia coli (131 strains), Staphylococcus aureus (62 strains), Enterococcus (59 strains), Pseudomonas aeruginosa (50 strains), Klebsiella pneumoniae (23 strains), Acinetobacter baumannii (18 strains), Enterobacter cloacae (17 strains), Proteus mirabilis (15 strains), Morganella morganii (15 strains) and Enterococcus faecalis (12 strains). The extended spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae were 102 and 17 strains, respectively. Methicillin-resistant Staphylococcus aureus were 60 strains. Conclusions Gram-negative bacteria were the main pathogens in patients with enterocutaneous fistula complicated with abdominal infection. The positive rate of the extended spectrum beta-lactamase is high. Most of the Staphylococcus aureus were resistant to Methicillin.