Serum cardiac troponin Ⅰ and lactic acid in neonatal patients with hypoxic-ischemic encephalopathy
- VernacularTitle:缺氧缺血性脑病新生儿血清肌钙蛋白Ⅰ和乳酸的变化
- Author:
Dongjie GUO
;
Guorui AN
;
Yufen WANG
;
Huazhong WANG
;
Haibin LIU
- Publication Type:Journal Article
- Keywords:
Hypoxia-ischemia,brain;
Troponin Ⅰ;
Lactic acid
- From:
Chinese Journal of General Practitioners
2008;7(10):714-715
- CountryChina
- Language:Chinese
-
Abstract:
Serum Cardiac troponin Ⅰ (cTn Ⅰ) and lactic acid were measured in 128 neonatal patients with hypoxic-ischemic encephalopathy and 38 healthy neonates (control group). Serum cTn Ⅰ and lactic acid levels were higher in neonates with hypoxic-ischemic encephalopathy than those in healthy neonates (P < 0. 05 ); and the differences of these values were also statistically significant between the serious patients and the mild patients (P<0.05). Serum cTn Ⅰ and lactic acid are two sensitive markers for degree of myocardial injury and hypoxia in neonatal patients with hypoxic-ischemic encephalopathy.