Short-term effects of combinant intraperitoneal hyperthermal chemotherapy with general chemotherapy in malignant ascites
- VernacularTitle:腹腔热灌注联合全身化疗在恶性腹腔积液控制中的近期疗效
- Author:
Zonglan HU
;
Junli CAO
;
Zhanzhao FU
;
Tao GU
;
Shaohui CHENG
;
Haixia HUA
;
Sen YANG
;
Lijiao ZHANG
;
Yanhong YANG
;
Lixin DONG
- Publication Type:Journal Article
- Keywords:
Chemotherapy,cancer,regional perfusion;
Ascites
- From:
Chinese Journal of General Practitioners
2008;7(10):701-702
- CountryChina
- Language:Chinese
-
Abstract:
Sixty-one patients with moderate to severe malignant ascites were enrolled and randomly assigned to receive intraperitoneal hyperthermal chemotherapy+intravenous chemical injection (treatment group; n=31) or routine intravenous chemical injection (control group; n=30). Short-term response and reverse effects were observed. Our results indicated that the complete remission rate, part remission rate,and clinical benefit rate in the treatment group was significantly higher than those in the control group (38.71% vs 13.33% ,41.94% vs 16. 67%, and 90.32% vs 66.67%, respectively). No difference in reverse effects was found between the two groups. Our data suggest that intraperitoneal hyperthermal chemotherapy plus general chemotherapy may effectively control the malignant ascites, and the reverse effects might be well tolerated.
