Effects of advanced glycation end-products on differentiation of vascular endothelial cells from bone marrow stem cells of mice
- VernacularTitle:晚期糖基化终末产物对小鼠骨髓干细胞向血管内皮细胞分化的影响
- Author:
Shufang XU
;
Yuming LI
;
Lulu CHEN
- Publication Type:Journal Article
- Keywords:
Glycation end-products,advanced;
Bone marrow stem cells;
Vascular endothelial cells;
Differentiation
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(5):548-549
- CountryChina
- Language:Chinese
-
Abstract:
The effects of advanced glycation end-products (AGEs) on number and activity of vascular endothelial cells (VEC) from hone marrow stem cells (BMSC) of mice were investigated. 100 μ/ml AGEs markedly inhibited differentiation of BMSC into VEC with decreased vascular endothelial growth factor receptor-2 positive cells, hut 20 μg/ml AGEs had no effect.
