Vascular endothelial growth factor and remedial angiogenesis
- VernacularTitle:血管内皮生长因子与治疗性血管生成研究进展
- Author:
Jing GUO
;
Lie WANG
- Publication Type:Journal Article
- Keywords:
vascular endothelial growth factor;
therapeutic;
angiogenesis
- From:
International Journal of Surgery
2008;35(10):675-678
- CountryChina
- Language:Chinese
-
Abstract:
Vascular endothelial growth factor (VEGF) is the endothelial cell-specific mitogen, facili-tates endothelial cell proliferation, increases vascular permeability and accelerates the formation of new blood vessels role. Angiogenesis is an important physiological and pathological significance of the process. In the human wound healing, inflammation, organ regeneration and tumor growth and metastasis, vascular prolifer-ative diseases, angiogenesis is an important role. Therapeutic angiogenesis is the use of inducible factor or vascular endothelial progenitor ceils, simulates in vivo angiogenesis mechanism, promotes angiogenesis and improves the collateral circulation. In this paper, VEGF and therapeutic ansiogenesis research progress were reviewed.
