Adenosquamous and squamous cell carcinoma of the gallbladder
- VernacularTitle:胆囊腺鳞癌和鳞癌与胆囊腺癌的临床对比研究
- Author:
Chunsheng HOU
;
Zhi XU
;
Lingfu ZHANG
;
Lixin WANG
;
Xiaofeng LING
;
Tonglin ZHANG
;
Xiaosi ZHOU
- Publication Type:Journal Article
- Keywords:
Gallbladder neoplasm;
Adenocarcinoma;
Neoplasms,squamous cell
- From:
Chinese Journal of General Surgery
2008;23(9):649-652
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explorethe clinical features of adenosquamous carcinoma,squamous cell carcinoma and adenocarcinoma of the gallbladder. Methods A retrospective analysis of 112 patients with gallbladder carcinoma was performed.The clinical features and outcomes of 11 patients with either adenosquamous or squamous cell carcinoma were compared with the other 101 patients of adenocarcinoma.Results The rate of tumor with T3 or T4 stage in adenosquamous/squamous cell carcinoma group and adenocarcinoma groupwere 100%and 53%(X2=7.013,P=0.008).The rate of distant metastasis in adenosquamous/squamous cell carcinoma group and edenocarcinoma at advanced stage(T3 or T4 stage)group were 0 and 35%(X2=3.900,P=0.048).The rate of lymph node invasion were 82% and 87%(X2=0.000,P=1.000).The rate of gastrointestinal tract invasion in adenosquamous/squamous cell carcinoma group and adenocarcinoma at advanced stage(T3 or T4 stage)group were 45% and 15%(X2=3.618,P=0.054).The median survival time for the two groups were 5 months and 4 months respectively(X2=0.359,P=0.549).Condusiom Adenosquamous/squamous cell carcinoma of the gallbladder had high local invasion capacity and usually were diagnosed at an advanced stage.The distant metastasis rate of adenosquamous/squamous cell carcinoma of the gallbladder was lower compared with adenocarcinoma.The lymph node invasion mte of adenosquamous/squamoua cell carcinoma was similar to adenocarcinoma.
