Role of BCL-2 family in cell autophagy
- VernacularTitle:Bcl-2在细胞自噬中的作用
- Author:
Shoucui LIU
;
Shanyu CUO
- Publication Type:Journal Article
- Keywords:
apoptosis;
autophagy;
Bcl-2
- From:
International Journal of Surgery
2008;35(10):701-704
- CountryChina
- Language:Chinese
-
Abstract:
Apoptosis, a mechanism of cell physiological death, is a kind of autonomic and order death process sequence-controlled by gene. Cell Autophngy is a kind process of serf-degrade, by enwraping cytosol and organelles, fusing with the lysosome, finally degrading lumen. There is complex relation between apop-tosis and autophngy. Autophngy can protect cells against death during stress, but it can also mediate cellular demise, depending on the specific circumstances. Bcl-2 family plays an intercross role apeptosis and autoph-ngy. This review focuses on the current research progress of the role of Bcl-2 family in cell autophagy.
