Diabetes associated cognitive impairment: a problem should not be ignored
- VernacularTitle:糖尿病性认知功能障碍:一个不容忽视的问题
- Author:
Jieying SU
;
Hongliang LI
;
Wenying YANG
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Cognitive impairment;
Glucotoxicity;
Lipotoxicity
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(5):476-479
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes can affect structure and function of brain in several aspects, but diabetic cognitive impairment is often ignored. The pathogenesis of diabetes associated cognitive impairment is complicated. Factors such as glucotoxicity, lipotoxicity, insulin resistance, hypoglycaemia and disturbance of Ca2 homeostasis may play important roles. Besides conventional diabetes therapy, new methods still need to be explored.
