The pathological role of placenta growth factor
- VernacularTitle:胎盘生长因子的病理学作用
- Author:
Chong ZHANG
;
Jiabang SUN
- Publication Type:Journal Article
- Keywords:
placenta growth factor;
pathology;
angiogenesis
- From:
International Journal of Surgery
2008;35(10):711-714
- CountryChina
- Language:Chinese
-
Abstract:
Angiogenesis is an important step during the occuring, development and metabsis of tumor which is regulated by some factors. PLGF is one of the VEGF family. It is homologous with VEGF-A, VEC,-FR-1 is its receptor. Although it expresses weakly during physiology. PLGF is an important pathologic angio-genesis factor at the condition such as anoxia, truma or tumor. Becanse its expression becomes strong at path-ologic cyophoria and many kinds of tumors, PLGF has a good value in clinic reasereh.
