Fasting plasma preptin levels and relevant factors in the subjects with different glucose tolerances
- VernacularTitle:不同糖耐量个体空腹血浆Preptin水平变化及其相关因素
- Author:
Yi TANG
;
Gangyi YANG
;
Ling LI
;
Ke LI
;
Wenwen CHEN
- Publication Type:Journal Article
- Keywords:
Preptin;
Diabetes mellitns,type 2;
Insulin resistance
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(5):527-528
- CountryChina
- Language:Chinese
-
Abstract:
Fasting plasma preptin level was assayed by RIA in the patients with different glucose tolerances. Regarding fasting plasma preptin levels, it was higher in females than in males. Fasting plasma preptin level was increased in patients with type 2 diabetes as compared with subjects of impaired glucose tolerance and normal controls, and there were positive correlations with diastolic blood pressure, blood triglyceride, total cholesterol, high-density lipoprotein-cholesterol, free fatty acids, 2 h plasma glucose after glucose load, HbA1C and HOMA-IR, suggesting a potential link between preptin and glucose-lipid metabolism and insulin resistance.