The molecular mechanism of astragalus polysaccharide in lowering blood-glucose and in affecting activity of PKB/Akt and translocation of GLUT4
- VernacularTitle:黄芪多糖降糖作用及其对蛋白激酶B和葡萄糖转运蛋白4的影响
- Author:
Jingfang ZHANG
- Publication Type:Journal Article
- Keywords:
Astragalus polysaccharide;
Lowering blood-glucose;
Protein kinase B;
Glucose transporter 4
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(5):546-547
- CountryChina
- Language:Chinese
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Abstract:
Astragalus polysaccharide (APS)was applied to treat rat model of type 2 diabetes mellitus.Blood glucose and insulin, the activity of PKB/Akt and translocation of GLUT4 in skeletal muscle of rats were examined. Results showed that AIMS decreased blood glucose, which may be related with increasing sensitivity of insulin, activity of PKB/Akt and transloeation of GLUT4 in the skeletal muscle tissue.
