Effects of levocaruitine on microinflammation stress status in maintenance hemodialysis patients
- VernacularTitle:左卡尼汀对维持性血液透析患者炎症状态的影响
- Author:
Chunhua CAO
;
Jun ZHU
;
Qiufeng HAN
- Publication Type:Journal Article
- Keywords:
Renal diatysis;
In flammation;
Levocarnitine
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(10):1669-1670
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect oflevecamitine on nutrition,microinflammation status in ma-intenance hemodialysis (MHD) patients. Methods Forty two MHD patients were selected, who had undergone he-modialysis for at least two months before the study. One gram of levoeamitine was injecfed to the patients at the end of each dialysis treatment for six months. The parameters of inflammation stress were studied. Results After treatment with levocarnitine for six months, the average levels of dry body weight decreased markedly. ( P<0.05 ), The aver-age serum levels of C2reaetive protein (CRP),interleuldn26 (IL26) ,tumor necrosis factor2α(TNF2α), (P<0.01 ). Difference was not significant between serum lipid parameters before and after the treatment. Conclusion Intravenous supplement with levocamitine in MHD patients, appears to be associated with an improvement of nutrition and mieroinflammation status.
