Churg-Strauss syndrome involving large-and medium-sized arteries: report of six cases and review of literature
- VernacularTitle:变应性肉芽肿性血管炎累及大中动脉六例报道并文献复习
- Author:
Dongzhou LIU
;
Yan ZHAO
;
Xiaofeng ZENG
;
Fengchun ZHANG
;
Yanhong TAN
;
Xiaoping HONG
;
Baodong SUN
;
Xuelv XIAO
- Publication Type:Journal Article
- Keywords:
Churg-Strauss Syndrome;
Artery,large-and medium-sized;
Stenosis;
Occlusion;
Thrombosis
- From:
Chinese Journal of Rheumatology
2008;12(10):697-700
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical manifestations and treatment of Churg-Strauss syndrome (CSS) involving large and medium-sized arteries. Method Six cases were investigated retrospec-tively and literature were reviewed. Results The pathological category of large-and medium-sized arteries involved in CSS included occlusion, stenosis, thrombesis, dissection, aneurysm, arteritis, and periarterifis. The involved arteries included coronary artery, central retinal artery, mesenteric artery, vertebral artery, basilar artery, carotid artery, aorta, and arteries of extremities. The large-and medium-sized arteries involvement in patients with CSS might not associated with age, duration of disease, and the titer of perinuclear-antineutrophil cytoplasmic antibodies. Treatment with corticosteroid and immunosuppressive agents combined with surgical interventions or anticoagulation if needed might improve the prognosis in the early stage. It was particularly hazardous for coronary involvement in patients with CSS. Conclusion CSS can involve many kinds of large-and medium-sized arteries. The pathological category of large and medium-sized arteries involved in CSS is diverse. More attention should be paid to large and medium-sized arteries involvement in patients with CSS.
