Effect of miRNA on biological characteristics of tumor
- VernacularTitle:miRNA对肿瘤生物学特性的影响
- Author:
Xiaofang XU
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Neoplasms;
Gene expression regulation;
Neoplastic processes;
Drug resist-ance,neoplasm
- From:
Journal of International Oncology
2008;35(10):747-750
- CountryChina
- Language:Chinese
-
Abstract:
Studies indicate that miRNAs correlate closely with tumorigenesis and tumor biological be-haviors, and play a significant role as a kind of regnlating factor in tumorigenesis, tumor cells proliferation, dif-ferentiation, apoptosis, invasion and metastasis, as well as in drug resistance of tumors. Further study of the targets and mechanisms of miRNA may be helpful to recognize the characterization of tumor biology and etiolo-gy, and bring new strategies for tumor therapy.