Correlation Between Plasma Homocysteine Concentration and Transient Ischemic Attack
- VernacularTitle:血浆同型半胱氨酸浓度与短暂性脑缺血发作的关系
- Author:
Peirong XIAO
;
Jianguo ZHONG
;
Haicun SHI
;
Yao WANG
;
Weigeng SONG
;
Guilong ZHOU
;
Yuan SHEN
;
Sheng SUN
;
Gendi WANG
- Publication Type:Journal Article
- Keywords:
homocysteine;
transient ischemic attack;
risk factor
- From:
International Journal of Cerebrovascular Diseases
2008;16(9):690-693
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between plasma homocysteine (Hcy) concentration and transient ischemic attack (TIA) and traditional vascular risk factors.Methods:The plasma Hcy concentrations of 112 patients with TIA and 62 controls were measured by fluorescenee polarization immunoassay.Hcy concentrations and related risk factors were analyzed.Results:The risk of TIA was increased significantly in plasma Hcy concentration 10.0 to 14.9 μmol/L group(OR=2.450,95% CI 1.091 to 5.502) and≥15.0 μmol/L group(OR=5.169,95% CI 2.096 to 12.746) compared with plasma Hcy concentration＜10.0 μmol/L group.Using TIA as the dependent wariable,various vascular risk factors (including plasma Hcy concentration) as the independent variable,logistic regression was analyzed.The result showed that the risk of TIA was increased significantly in plasma Hcy concentration＞10.0 μmol/L group compared with plasma Hcy concentration＜10.0 μmol/L group(OR=3.150,95% CI 1.380 to 7.192).Conclusions:Plasma Hcy concentration is an independent risk factor for TIA.
