Advances in the research of decellularization of tissues and organs
- VernacularTitle:组织器官去细胞的研究进展
- Author:
Junjie LV
;
Wei WANG
- Publication Type:Journal Article
- Keywords:
Decellularization;
Extracellular matrix;
Tissue engineering;
Scaffolds
- From:
International Journal of Biomedical Engineering
2008;31(5):316-320
- CountryChina
- Language:Chinese
-
Abstract:
Decellularized tissues and organs have been widely used in tissue engineering and regenerative medicine applications. The efficiency of cell removal from a tissue depends on the origin of the tissue and the methods applied. Each of these treatment affects the biochemical composition, tissue ultrastructure, and mechanical behavior of the remaining scaffold, which in turn, affect the host response to the material. Herein, we made a review about the most commonly used decellularization methods and their effects upon biologic scaffolds.
