Progression of stathmin
- VernacularTitle:Stathmin蛋白的研究进展
- Author:
Yan WANG
- Publication Type:Journal Article
- Keywords:
Stathmin;
Neoplasms;
Cell cycle
- From:
Journal of International Oncology
2008;35(10):738-740
- CountryChina
- Language:Chinese
-
Abstract:
Many transcription factors, kinases and phosphorylase regulate the expression and activity of stuthmin. The abnormality of stathmin expression or its activity is closely involved in lots of pathological or phys-iological events such as cell proliferation, development of tumor. Many kinds of malignant tumors have high ex-pression of stathmin, and inhibiting the expression of stathmin protein is a new biotherapy target in tumor geneth-erapy. Moreover, stathmin protein can influence curative effect of some chemotherapeutics ,which target microtu-bular. This has some significance with regard to the guidance of clinical medication.
