Regulating mechanisms of homeohox gene HOXA7 in tumor genesis and development
- VernacularTitle:同源异型盒A7基因在肿瘤发生发展中的调控机制
- Author:
Ye HAN
- Publication Type:Journal Article
- Keywords:
HOXA7;
Neoplasms;
Gene silencing
- From:
Journal of International Oncology
2008;35(10):741-743
- CountryChina
- Language:Chinese
-
Abstract:
Homeobex gene,derived firstly from Drosophila, has the ability of regulating normal embry-onic development and proliferation and differentiation of adult tissue cells. Recent studies demonstrate that HOXA7 can be high and low expressed in adult tumor tissues by means of genetic fusion and genetic silencing to regulate genesis and development of tumor cells. To study its expression and regulation in tumor will be helpful for tumor diagnosis ,treatment and prognosis.
