Development of triple-negative breast cancer
- VernacularTitle:三阴乳腺癌研究进展
- Author:
Xiaolan WANG
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Therapy;
Triple- negative
- From:
Journal of International Oncology
2008;35(10):767-771
- CountryChina
- Language:Chinese
-
Abstract:
Triple-negative breast cancer is defined as one of the subtypes of breast cancer recently. At present, no effective tailored therapies have been developed for patients with triple-negative breast cancer, chemotherapy is the main modality of systemic therapy for patients of this subtype. However, compared with non-TNBC, sueh treatment has a high rate of local and systemic relapse. Histologically, such cancers are poorly differentiated, and most fall into the basal- like subgroup of breast cancers. Triple- negative breast cancers have many similarities to BRCA1-associated breast cancers.
