Idiotype-pulsed dendritic cells in multiple myeloma immunotherapy
- VernacularTitle:独特型蛋白致敏的树突细胞瘤苗治疗多发性骨髓瘤
- Author:
Liangliang MA
- Publication Type:Journal Article
- Keywords:
Dendritic cells;
Multiple myeloma;
Immunoglobulin idiotypes
- From:
Journal of International Oncology
2008;35(10):789-792
- CountryChina
- Language:Chinese
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Abstract:
The idiotype of the monoclonal immunoglobulin expressed by multiple myeloma provides a tumor-specific antigen. Vaccination with idiotype-pulsed dendritic cells has expansive prospect to eliminate the minimal residual disease, prolong disease-free survival of multiple myeloma patients. It' s application in anti-tumor immunotherapy has become the focus of active and specific immunotherapy of tumors.
