Clinical analysis of nosocomial infection in patients with non-Hodgkin lymphoma
- VernacularTitle:非霍奇金淋巴瘤患者合并医院感染的临床分析
- Author:
Suying QIAN
;
Zhi FANG
;
Yamin CHEN
;
Ningning WU
;
Jianfen XU
;
Zhaoxiong XIA
;
Xiangmin TONG
- Publication Type:Journal Article
- Keywords:
Non-Hodgkin lymphoma;
Nosocomial infection;
Gram-negative bacteria
- From:
Chinese Journal of Clinical Infectious Diseases
2008;1(4):219-221
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify risk factors and preventive measures of nosoconial infections in patients with non-Hodgkin lymphoma (NHL). Methods Clinical data of 65 NHL patients admitted from January to December 2007 were retrospectively analyzed. Results According to WHO classification (2001), 58 patients were with B-cell lymphoma, 7 were with T-cell lymphorna. All patients received CHOP regimen as initial chemotherapy and 23 of them were with nosecomial infections. Logistic regression analysis demonstrated that age, length of stay, pathological type, bone marrow involvement, levels of serum lactate dehydrogenase (LDH), beta2-microglobulin and invasive treatment were identified as risk factors of nosocomial infections. Respiratory tract infections and infections with gram-negative microorganisms were the most popular. Conclusion High nosocomial infection rate is found in NHL patients, and control of risk factors may effectively prevent nosocomial infections in NHL patients.
