Advances in studies on the application of platelet-rich plasma in the field of orthopedicsand the underlying mechanisms
- VernacularTitle:富血小板血浆的作用机制及其骨科临床应用进展
- Author:
Weitao JIA
;
Changqing ZHANG
- Publication Type:Journal Article
- Keywords:
Platelet-rich plasma;
Growth factor;
Mechanism of action;
Tranma repair
- From:
International Journal of Biomedical Engineering
2008;31(5):297-301
- CountryChina
- Language:Chinese
-
Abstract:
Platelet-rich plasma(PRP) is a highly-concentrated plasma enriched in platelets and various growth factors. These growth factors will be released abundantly by platelets when PRP is activated by thrombin, which plays a key role in accelerating wound healing, bone repair, and meanwhile, in controlling of inflammatory process. Biocompatibility and versatility of PRP have been confirmed in clinical studies as well as its excellent effects on tissue reparation. These have lead to the extensive use of PRP in many medical fields as a therapeutic alternative. Mechanism of PRP in bone and tissue repair the application of PRP in the field of orthopedics is reviewed in this article. In addition, attempt is made to discuss about some problems still existing in the clinical application of PRP.
