Comparison between transabdominal and transcervical chorionic villus sampling in clinical application for prenatal diagnosis
- VernacularTitle:两种途径绒毛活检在产前诊断中应用的比较
- Author:
Yanmin LUO
;
Qun FANG
;
Yongzhong YANG
;
Junhong CHEN
;
Minling CHEN
;
Yongzhen CHEN
- Publication Type:Journal Article
- Keywords:
Pregnancy trimester,first;
Chorionic villi sampling;
Prenatal diagnosis;
Pregnancy,multiple
- From:
Chinese Journal of Obstetrics and Gynecology
2008;43(11):814-817
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare transabdominal and transcervical chorionic villus sampling (TC-CVS) in application for prenatal diagnosis, and to summarize the experience of transabdominal chorionlc villus sampling (TA-CVS). Methods One hundred and nine TA-CVS between April 2005 and November 2007 and 69 TC-CVS between August 1999 and March 2005 were retrospectively analyzed. Results ( 1 ) The mean gestational age was (12.4±1.9) weeks at TA-CVS and (8.8±1.2) weeks at TC-CVS (P< 0.01). (2) Compared with TC-CVS, punctures were fewer (1.4±0.5) and (1.1±0.4) and specimen amount was more (9±5) mg and (17±5) mg in TA-CVS, and the success rate of one puncture (62.3% vs 87.2% ) was higher in TA-CVS. (3)Among the cases followed up, the incidence of vaginal bleeding(TA-CVS: 2 eases, 2.0% ; TC-CVS: 2 cases, 6.1% ) and spontaneous abortion (TA-CVS: 4 cases, 4.0%; TC-CVS: 1 cases, 3.0%) were not significantly different between the two groups(P>0.05).Conclusion TA-CVS appears to be a good method for early prenatal diagnosis with a wide range of indications, high success rate and sufficient specimen.
