Clinical analysis of comb interferon curing 74 patients with chronic hepatitis C
- VernacularTitle:复合干扰素联合利巴韦林治疗难治性慢性丙型肝炎74例疗效分析
- Author:
Xizeng ZHU
;
Xudong PEI
;
Huaihong ZHANG
- Publication Type:Journal Article
- Keywords:
Hepatitis C,chronic;
Interferons;
Ribavirin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(9):1465-1466
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of comb interferon( comb interferon CITF) uniting virazole to cure recurring or non-responding chronic hepatitis C.Methods Hypodermic comb "interferon 15μg,3 times every week,subcutaneously injected,24 weeks course of treatment was adminstered to 74 patients of recurring or non-responding chronic hepatitis C.Clinical symptom,physical sign,ALT,hepatovirus continual response rate and the condition of adverse effect were observed during treatment,chron-culminate,follow to 6 months' withdrawl.Results 72 patients accomplished treatment,HCV-RNA of recurring group and non-responding group to continual negative change rate were 73% and 37% (P＜0.05)after treatment termination,without severity adverse reaction being found.Condusion Comb interferon 15 μg/d combining virazole 900mg/d have better curative effect in curing recurring or nonresponding chronic hepatitis C.
