Mismatch repair in hereditary nonpolyposis colorectal cancer
- VernacularTitle:错配修复在遗传性非息肉性结直肠癌中的研究进展
- Author:
Huixian XU
;
Xiabiao PENG
;
Xingxiang HE
- Publication Type:Journal Article
- Keywords:
mismatch repair;
hereditary nonpolyposis eolorectal cancer;
gene
- From:
International Journal of Surgery
2008;35(11):745-748
- CountryChina
- Language:Chinese
-
Abstract:
Hereditary nonpolyposis colorectal cancer as a eolorectal cancer is of most hereditary characters.With developing of the molecular genetics on detection technology,mismatch repair gene has already been detected by multi-approach,and been applied to screen hereditary nonpolyposis eolorectal cancer patients.In this artical,we mainly discuss the correlated study progression between hereditary nonpolyposis eolorectal cancer and several mismatch repair genes such as MSH2,MLH1,MSH6,PMS1,PMS2,MLH3 and EXO1.
