Resistance mechanism of imatinib therapy in gastrointestinal stromal tumors
- VernacularTitle:伊马替尼治疗胃肠间质瘤的耐药机制
- Author:
Qian XIAO
;
Kefeng DING
- Publication Type:Journal Article
- Keywords:
gastrointestinal stromal tumors;
imatinib;
resistance
- From:
International Journal of Surgery
2008;35(11):754-756
- CountryChina
- Language:Chinese
-
Abstract:
Imatinib,a small-molecule kinase inhibitor,has proven useful in the treatment of recurrent or metastatic gastrointestinal stromal tumors ,However,resistance to imatinib is a more and more serious problem.This review summarizes the existing knowledge of the imatinib resistance mechanism in gastrointestinal stromal tumors and describes the treatment directions in further.
