Application value of urokinase in sclerotherapy of endometrial cystoma of ovary under ultrasonic guidance
- VernacularTitle:尿激酶在超声引导卵巢子宫内膜异位囊肿硬化治疗中的应用价值
- Author:
Yongjie LI
;
Junhua ZHANG
;
Dong LI
;
Yingying ZHAO
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Ovarian cysts;
Endometriosis;
Urinary plasminogen activator
- From:
Chinese Journal of Ultrasonography
2008;17(11):973-976
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the application value of urokinase in sclerotherapy of endometrial cystoma of ovary under ultrasonic guidance.Methods According to the sonographic characteristics,156 endometrial cystomas of ovary in 148 cases were divided into four types:the type of simple cyst(E1),the type filled with homogeneous echoes(E2),the type of multilocular endometrioma(E3)and the type mingled with solid in it(E4).Under ultrasonic guidance,the patients underwent selerotherapy with absolute alcohol after the cystomas washed repectively with urokinase(treatment group)and normal saline(control group).The recovery ratios and the remission of dysmenorrhea were observed.Results The recovery ratio,excellence ratio and inefficiency ratio of treatment group were 94.9%,5.1%and 0 respectively,while those of control group 76.9%,11.5%and 1 1.5%respectively.As to the recovery ratios,there were no statistical differences among types in treatment group.While the differences between E3,E4 and E1,E2 were significant (P＜0.05,P＜0.01).As to E3 and E4,there were statistical differences between the two groups(P＜0.01,P＜0.05).After 6 months'therapy,according to the visual analogue scales of dysmenorrhea,there was statistical difference between the two groups(t=7.802,P＜0.001).Conclusions Using urokinase to thoroughly dissolve and wash cellulose and mural blood clots in endometrial cystoma of ovary before the injection of sclerosing agent can definitely improve the recovery ratio and remit the symptoms of dysmenorrhea.
