Collagen Genes and Intracranial Aneurysm
- VernacularTitle:胶原蛋白基因与颅内动脉瘤
- Author:
Gang CUI
;
Baojin ZHAI
;
Derang JIAO
- Publication Type:Journal Article
- Keywords:
collagen;
intracranial aneurysm;
gene
- From:
International Journal of Cerebrovascular Diseases
2008;16(10):791-793
- CountryChina
- Language:Chinese
-
Abstract:
Intracranial aneurysm often result from congenital defects of regional cerebral artery wall and increased endovascular pressure.Its occurrence and development are associated with several risk factors including genetics,smoking,hypertension,cerebral atherosclerosis and vasculitis.With the application of gene chip technology for the past few years,the research of pathogenic genes associated with intracranial aneurysms was further deepened,and some susceptibility genes closely associated with the occurrence of intracranial aneurysms have been found,and this suggests that intracranial aneurysm may be a polygenic disease caused by the combined action of multiple genes.
