The clinical characteristics of interstitial lung disease in patients with dermatomyositis and polymyositis
- VernacularTitle:皮肌炎多发性肌炎患者间质性肺病病理资料推断性分析
- Author:
Peizhen WANG
;
Jianlong GUAN
;
Lizhi BAO
;
Jingming LI
;
Xinghai HAN
- Publication Type:Journal Article
- Keywords:
Polymyositis;
Dermatomyositis;
Lung diseases,interstitial;
Tomography,X-ray computed
- From:
Chinese Journal of Rheumatology
2008;12(12):826-828
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical features,and prognosis of the interstitial lung disease (ILD) in patients with dermatomyositis (DM) and polymyositis (PM) by chest X-ray,chest high-resolution CT scan (HRCT) and pulmonary lung function.Methods Thirty-three patients hospitalized with DM/PM associated ILD were retrospectively analyzed.Results Thirty-three patients with ILD were confirmed by HRCT.Abnormal pulmonary function tests were available in 82% of patients.Clinical-imaging analysis revealed that the pathological features of ILD were non-specific interstitial pneumonia (NSIP,57%) and unusual interstitial pneumonia (UIP,25%).UIP types showed a poor prognosis and high mortality (70%).Conclusion This study shows that HRCT is more sensitive for the diagnosis of ILD than lung function tests and chest X-ray.Combined HRCT and chest X-ray with lung function tests and blood gas analysis have shown that the major pathological types of ILD are NSIP and UIP,in which UIP are associated with high mortality and poor prognosis.
