An association between glucose metabolism status and brachial-ankle pulse wave velocity in Chinese patients with coronary artery disease
- VernacularTitle:冠心病患者糖代谢状态对脉搏波速度影响研究
- Author:
Jiajia SHEN
;
Yongquan WU
;
Jue LI
;
Dayi HU
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Blood slncose;
Pulse wave velocity
- From:
Chinese Journal of Internal Medicine
2008;47(12):995-998
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between glucose metabolism status and brachial-ankle pulse wave velocity(baPWV)in Chinese patients with coronary artery disease(CAD).Methods baPWV values were measured in 198 CAD patients.Plasma glncose,serum lipids,hsCRP and other baseline data were obtained in all the patients.According to the glucose level,the participants were divided into 3 groups:normal glucose tolerance(NGT)group,impaired glucose regulation(IGR)group and diabetes mellitus(DM)group.ResultsbaPWV values in the DM group(1807±381)cm/s were significantly higher than those in the NGT group[(1615±248)cm/s,P=0.000]and IGR group[(1674±277)cm/s.P=0.035].Multiple stepwise linear regression analyses indicated that higher baPWv values were associated with aging and hsCRP levels in 198 patients.In DM group,higher baPWV values were independently associated with aging and HbA1 C levels.Conclusions In patients with coronary artery disease.baPWV values increase with different glucose metabolism status from NGT to IGR then DM.baPWV values in the patients with DM were significantly higher than those in the other two groups.Glycemic control may ameliorate arterial stiffness.
