The clinical observation of local intraarterial thrombolysis in acute ischemic stroke of the anterior circulation
- VernacularTitle:局部动脉溶栓治疗急性前循环脑梗死临床观察
- Author:
Xiaoxin BAI
;
Shengping HUANG
;
Tielin LI
;
Hao LIN
;
Wangchi LUO
;
Xuelian LI
;
Wenyan ZHU
;
Yefeng CAI
;
Yan HUANG
- Publication Type:Journal Article
- Keywords:
Cerebral infarct;
Thrombolysis;
Intervention treatment
- From:
Clinical Medicine of China
2008;24(12):1210-1213
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the short-term outcome of local intraarterial thrombolysis in patients with acute ischemic stroke of the anterior circulation. Methods 24 patients with acute ischemic stroke of the anterior cir-culation within 8 hours were treated by local intraarterial thrombolysis. Arterial recanalization was divided into total, partial and occlusive respectively according to angiography. Evaluation of clinical outcome was performed on the 30th day after thrombolysis,and was classified as good for Modified Rankin Scale (MRS) scores of 0 to Ⅲ and poor for MRS scores of Ⅳ to Ⅵ. Results Total recanalization was obtained in 54.2 % of patients, partial recanalization in 25.0%. Clinical outcome was good in 15 patients (62.5%). Cerebral hemorrhage occurred in 4 patients (16.7%). Four patients died (16.7%). Conclusion Local intraarterial thrombolysis is an effective method for treatment of a-cute iachemic stroke of the anterior circulation. It needs further practice and long-term follow-up study on safety and long-term efficacy.
