The changes of blood coagulation indices after percutaneous coronary intervention
- VernacularTitle:急性冠状动脉综合征冠状动脉支架置入术凝血指标变化
- Author:
Jun WU
;
Min YANG
;
Jie ZHAO
;
Zheng ZHANG
- Publication Type:Journal Article
- Keywords:
Acute coronary syndrome;
Percutaneous Coronary Intervention;
Thrombin;
Antithrom-bin;
Protein C
- From:
Clinical Medicine of China
2008;24(12):1217-1219
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of blood coagulation indices during the percutaneous cor-onary intervention(PCI), so as to provide evidence for anticoagulation therapy. Methods 34 acute coronary syn-drome patients were enrolled,whose blood sample was taken at baseline,1 h,4 h,24 h,and 48 h after PCI operation. Thrombin-antithrombin complex(TAT), vWF, protein C, antithrombin, fibrinogen, D-dimer were tested. The result was processed by statistical software. Results After PCI, TAT continued to rise, protein C and antithrombin drop down,the vWF and D-dimer rose with TAT,and fibrinogen transiently drop down. Conclusion The thrombin pro-duces more quickly after PCI,its time phrase is coordinated with vWF and D-dimer,at the same time the anticoagula-tion system drops down. High anticoagulation at least maintains within 48 h and then tends to be normal.
