Exploration of cut-off value of TSH during screening of congenital hypothyroidism in the newborns
- VernacularTitle:新生儿先天性甲状腺功能减退症筛查中TSH切值的探讨
- Author:
Xiaoxiao CHEN
;
Yufeng QIN
;
Yiping QU
;
Huaqing MAO
;
Yuhua SHI
;
Zhengyan ZHAO
- Publication Type:Journal Article
- Keywords:
Newborn screening;
Hypothyroidism;
Thyrotropin;
Reference values
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(6):639-640
- CountryChina
- Language:Chinese
-
Abstract:
Positive linear correlation was found between TSH level and detection rate of congenital hypothyroidism (CH). When measured with a cut-off point at 9, 10, 15 and 20 mU/L of TSH, the sensitivity of positive detection rate for CH was 99.77%, 96.80%, 81.25% and 71.88%, respectively. TSH > 9 mU/L seems to be a reasonable cut-off value.