Application of microarray technique in gene expression analysis of pancreatic islets in pregnant rats
- VernacularTitle:应用基因芯片技术研究大鼠妊娠期胰岛基因表达谱的变化
- Author:
Ying XUE
;
Cuiping LIU
;
Qingxin YUAN
;
Kuanfeng XU
;
Yu XU
;
Xiaodong MAO
;
Guofang CHEN
;
Chao LIU
- Publication Type:Journal Article
- Keywords:
Pregnancy;
Gene expression;
Oligonucleotide array sequence analysis;
Islet regeneration
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(6):658-659
- CountryChina
- Language:Chinese
-
Abstract:
Genechip was applied to explore gene expression profile of islets in rats at various stages of pregnancy. Compared with the normal control group, differential expressions of hundreds of genes were detected during pregnancy. Reg3α gene expression was markedly increased during pregnancy, which may be related to islet regeneration.