Interaction between hepatic stellate cells and hepatocellular carcinoma
- VernacularTitle:肝星状细胞和肝细胞癌的相互作用
- Author:
Yunhong XIA
- Publication Type:Journal Article
- Keywords:
Carcinoma,hepatocellular;
Astrocytes;
Cell communication
- From:
Journal of International Oncology
2008;35(11):845-848
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic stellate cells(HSCs)are key sources of extraeellular matrix during liver fibrosis and in normal liver.During chronic injury,HSCs transform into myofibroblast-like cells,causing liver fibrosis.Hepatocellular carcinoma iS multiple factors disease.There are considerable HSCs infihration in the extracellular matrix of hepatocellular carcinoma.Investigation the interaction between HSCs and hepatocellular carcinoma Can provide a new thinking of hepatocellular carcinoma therapy.