Research advances in thermochemotherapy of drug-loaded magnetic micro/nano-particles
- VernacularTitle:磁性载药微球应用于热化疗的研究进展
- Author:
Na XU
- Publication Type:Journal Article
- Keywords:
Hyperthermia,Induced;
Drug Therapy;
Drug-loaded Magnetic Micro/nano-particles
- From:
Journal of International Oncology
2008;35(11):860-863
- CountryChina
- Language:Chinese
-
Abstract:
Thermochemotherapy by drug-loaded magnetic micro/nano-particles is attracting increasing attention because it combines the advantages of chemotherapy and high targeting and selectivity of hyperthermia,especially intra-cellular hyperthermia.Magnetic micro/nano-particles,usually consisting of biodegradable pely-mers matrics co-incorporated with ferromagnetic particles and anti-cancer drugs,will generate heat when exposed to an externally applied alternating magnetic fields due to electromagnetic induction by ferro-particles,in the meanwhile,sensitivity of anti-cancer drug will be greatly enhanced by higher temperature.Tumors will greatly suppressed by the synergetic effect of chemotherapy and targeted hyperthermia.
