Study of enhancer in gene expression regulation
10.3760/cma.j.issn.1673-422X.2011.03.004
- VernacularTitle:增强子对基因表达调控的研究进展
- Author:
Guochao GE
;
Xiaopeng CHEN
- Publication Type:Journal Article
- Keywords:
Enhancer elements(genetics);
Gene expressions regulation,neoplasms;
Computational biology
- From:
Journal of International Oncology
2011;38(3):173-175
- CountryChina
- Language:Chinese
-
Abstract:
Enhancers are cis-acting elements of DNA which can enhance the transcription activity of promotors.Emerge of Bioinformatics brings great convenience for enhancers investigation.The utilization of tumor-specific promotors modified by enhancers to make the expression of theoretical gene or effector in specified organisms or cells,and to implement targeted therapy of tumor,is a significant and potential gene therapy method.