Routine fetal screening for congenital heart diseases: the detection rate in the high-risk and low-risk population
- VernacularTitle:胎儿心脏畸形在高危与低危孕妇中超声检出率的研究
- Author:
Ling ZANG
;
Ying WU
;
Feng SUN
;
Tao LIU
- Publication Type:Journal Article
- Keywords:
Ultrasonography,prenatal;
Heart defects,congenital;
Pregnancy,high-risk
- From:Chinese Journal of Ultrasonography
2008;17(12):1038-1040
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide basis for routine fetal cardiac screening by comparing the ultrasound detection rate of fetal heart defects between the high-risk and low-risk population.Methods According to the questionnaire about maternal risk factors,all 7165 pregnant women were divided into two groups.The high-risk group included 2147 cases and the remained 5018 were considered as low-risk population.Routine fetal heart screening was performed by the four-chamber view,left and right outflow tract views.If some cardiac malformations were found,the detailed fetal echocardiography would be performed.Both the detection rate of fetal cardiac defects and distribution of the relevant risk factors were analyzed.Results Ninty-five(1.33%)cases of congenital heart disease were found in our study,32(1.49%)cases from highrisk group and 63(1.26%)cases from low-risk group.No significant was found between the two groups (X2=0.635,P＞0.05).Karyotyping were performed prenatally in 23 of 95 fetal congenital defects cases by cordocentesis and chorionbiopsy,and 11(47.83%)cases of concomitant chromosomal abnormality were found.Conclusions Routine fetal screening for congenital fetal diseases should be performed in non-selected population for the similar detection rate of fetal defect in high-risk and low-risk group.
