The early diagnostic value of olfactory function measurement to Alzheimer disease
- VernacularTitle:嗅觉功能检测对阿尔茨海默病的早期诊断价值
- Author:
Xichi JU
;
Qiumin QU
;
Wei WANG
;
Qian WU
;
Guogang LUO
- Publication Type:Journal Article
- Keywords:
Smell;
Alzheimer disease;
Cognition disorders
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(36):9-11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the early diagnostic value of olfactory function measurement to Alzheimer disease (AD). Method Detected the thresholds of detectability, identification threshold with pictu.re-based odor identification test in 21 AD patients (AD group) and 21 healthy elderly people (control group), and evaluated the relationship with mini-mental state examination (MMSE). Results AD group was impaired on threshglds of detectability [(1.81±0.75) scores], identification threshold [(2.48±0.68) scores]compared with control group [(1.24±0.89) scores and (2.00±0.71) scores, P< 0.05]. The thres holds of detectability and identification threshold were related to MMSE in AD group (r =-0.50,-0.54, P< 0.01). Conclusion The early diagnostic value of olfactory function measurement to AD is very great.
