Significance of the activation of blood platelet and hepatic and renal function in patients with pre-eclampsia and eclampsia
- VernacularTitle:子痫前期及子痫患者血小板活化和肝肾功能检测的意义
- Author:
Qi LIAO
;
Xiaoyan MA
;
Mingyang ZHENG
;
Manhua CUI
;
Chao LIU
- Publication Type:Journal Article
- Keywords:
Platelet membrane glycoproteins;
Receptors,fibrinogen;
Eclampsia
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(36):11-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the role of platelet-actived factors and hepatic and renal function in the development of pre-eclampsia and eclampsia by detecting the levels of the GP Ⅱb/Ⅲa in the blood, Pt and hepatic and renal function of the patients with pre-eclampsia and eclampsia. Method GP Ⅱb/Ⅲa, Pt and hepatic and renal function were measured in the normal non-pregnancy women, normal late-pregnancy women and pre-eclampsia and eclampsia women. Results The level of GP Ⅱb/Ⅲa in patients with severe pre-eclampsia and eclampsia was higher than that in non-pregnancy, normal late-pregnancy and mild pre-eclampsia (P<0.01). The count of Pt in patients with severe pre-eclampsia and eclampsia was lower than that in non-pregnancy, normal late-pregnancy and mild pre-eclampsia (P<0.01). Except ALB, the hepatic and renal function had significant difference among severe pre-eclampsia and eclampsia, normal late-pregnancy and mild pre-eclampsia. Conclusion Detecting the GP Ⅱb/Ⅲa, Pt and hepatic and renal function have clinical significance in severe pre-eclampsia and eclampsia.
