Determination of serum resistin and high-sensitivity C-reactive protein in patients with idiopathic sudden sensorineural hearing loss and their clinical significance
- VernacularTitle:抵抗素和高敏C-反应蛋白在突发性耳聋中的临床意义
- Author:
Shanli NIU
- Publication Type:Journal Article
- Keywords:
Resistin;
Hearing loss,sudden;
C-reactive protein
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(36):17-19
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the role of serum resistin and high-sensitivity C-reactive protein (hs-CRP) in idiopathic sudden sensorineural hearing loss. Methods The levels resistin and hs-CRP were determined in the 102 idiopathic sudden sensorineural hearing loss patients who were observed at two differ-ent time points: before and after treatment, and 35 patients with other neurologic diseases and 30 healthy people were used as control. Results The levels resistin and hs-CRP in serum of patients with idiopathic sudden sensorineural hearing loss were markedly higher than those in the controls (P< 0.01). The levels of resistin and ha-CRP in the patients with idiopathic sudden sensorineural hearing loss after treatment were significantly less than those before treatment. There was a correlation between serum resistin and hs-CRP in patients with idiopathic sudden senserineural hearing loss (r=0.65, P<0.01). Conclusion The levels of serum resistin and hs-CRP have instructive significance in idiopathic sudden sensorineural hearing loss treating and prognosis estimating.
