Clinical analysis of 120 cases of infective endocarditis
10.3760/cma.j.issn.0578-1426.2009.01.011
- VernacularTitle:感染性心内膜炎120例临床分析
- Author:
Xiufen LOU
;
Deyan YANG
;
Zhengyin LIU
;
Huanling WANG
;
Taisheng LI
- Publication Type:Journal Article
- Keywords:
Endocarditis,bacterial;
Echocardiography
- From:
Chinese Journal of Internal Medicine
2009;48(1):35-38
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the diagnosis and treatment of infective endocarditis(IE)by exploring its causes,pathogenic microorganism and clinicsI characteristics.Methods The clinical data of 120 IE patients treated in Peking Union Medical College Hospital from October 1997 to September 2007 were analyzed retrospectively.Results Of the 120 consecutive cascs diagnosed as IE according to the Duke's new criteria,79 were male and 41 female with a average age of(43.2±16.7)years old.Twelve cases were prosthetic valve endocarditis(PVE)and 108 cases native valve endocarditis(NVE)and there were no previously known heart diseases in 29 of the cases.Seventy-nine of the 108(73.1%)NVE patients had basic cardiac abnormalifies before IE diagnosis,such as congenital cardiovascular disease(30 cases),idiopathic mitral valve prolapse(23 cases)and rheumatic heart disease(11 cases).Fever(100.0%),anemia(54.2%)and embolism(48.3%)were the most common clinical manifestations in the IE development.Of the 83 patients who had a positive blood culture result,Streptococcus vividaus(51.8%)was the most common isolated microorganism.Conclusions Congenital cardiovascular diseases and idiopathic mitral valve prolapse are the two most commonly heart diseases in IE.Blood culture and echocardiogram should always be done to exclude IE,especially presenting with fever of unknown reasons.
