Evaluation of hepatic radiofrequency ablation by contrast enhanced intraoperative ultrasound
- VernacularTitle:术中超声造影评价肝射频消融效果的实验研究
- Author:
Kai LI
;
Erjiao XU
;
Rongqin ZHENG
;
Jie REN
;
Ren MAO
;
Aohua ZHANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Mierobubbles;
Catheter ablation;
Liver
- From:
Chinese Journal of Ultrasonography
2008;17(12):1079-1081
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the use of contrast enhanced intraoperative uhrasound(CE-IOUS) in evaluating hepatic radiofrequency ablation(RFA)lesions.Methods Fifteen RFA lesions in twelve dogs were examined by IOUS and CE-IOUS 15 min and 30 min after RFA.IOUS and CE-IOUS images were compared with RFA specimen stained by TTC.Results Satisfactory images could be achieved bv CE-IOUS at 15 rain after RFA.Compared with IOUS,CE IOUS could depict the border of RFA lesions more clearly (P<0.01).In CE-IOUS,93.3%(12/13)of RFA lesion images were consistent with that of TTC in shape,while in IOUS,only 13.3%(2/15)of the images were consistent with that of TTC in shape.The average areas of RFA lesions cross-section measured by IOUS,CE-IOUS and TTC were(4.82±1.49)cm2,(3.48±1.25)cm2 and(2.93±0.87)cm2.Statistical significance was found between the areas shown by IOUS and TTC staining(P=0.000),as well as between CE-IOUS and TTC staining(P=0.027).The areas shown by IOUS and TTC were not linear correlated(r=0.28,P=0.316),but the areas shown bv CE IOUS and TTC were wetl correlated(r=0.75,P=0.002). Conclusions CE-IOUS is a promising method for evaluating intraoperative RFA lesions and worthy of further clinical research.