Lung protective strategies of ventilation in hyaline membrane disease of neonates
- VernacularTitle:允许性高碳酸血症在新生儿肺透明膜病的应用
- Author:
Xiufang YANG
;
Kaijun ZHENG
;
Ronghua XIA
;
Jingguo CHEN
;
Jian CHEN
;
Huijuan HUANG
- Publication Type:Journal Article
- Keywords:
Hyaline membrane disease;
Machanical ventilation;
Lung protective;
Ventilation strategies;
Infant,newborn
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(12):2002-2004
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the protective ventilation strategies in hyaline membmne disease(HMD) of neonates,in order to decrease the incidence of ventilator-associated lung injury(VAU).Methods 68 newborn infants,diagnosed as of neonatal hyaline membrane disease and needed ventilator support,were recruited from the neonatal intensive care unit from 2003 to 2005.Infant with HMD were divided into the conventional ventilation practice group (the control group) and protective ventilation strategies group (the experimental group).The ventilator settinns,artery blood gas analysis,ventilator-associated lung injury and other clinical data were analyzed and compared.Results The incidence of ventilator-associated lung injury in the experimental group wag significantly lower than that in the cntrol group(2.94% VS 17.6%,P＜0.05).PaCO2 in experimental group was significantly higher than that in control group.The mortality in the experimental group was significantly lower than that in control group.Condusion The protective ventilation strategies can decrease the incidence of ventilator-associated lung injury in neonatal HMD.the protective ventilation strategies can decrease the mortality in neonatal HMD.
