Leptin and osteoarthritis
10.3760/cma.j.issn.1673-4203.2009.01.024
- VernacularTitle:瘦素与骨关节炎
- Author:
De LI
;
Wei SONG
- Publication Type:Journal Article
- Keywords:
leptin;
ostecarthritis;
chondrocyte
- From:
International Journal of Surgery
2009;36(1):63-66
- CountryChina
- Language:Chinese
-
Abstract:
Leptin,the product of the obese gene,is a 16kDa secreted protein produced by white adipocytes.Because of its dual nature as a hormone and cytokine,leptin plays a role in regulating energy metabolism,inflam-marion,immune response,neuroendocrine and angiogenesis,and so on.The review focuses on the research and controversy of leptin's effect in osteoarthritis.
